Presents a mix of interrelated stories: a Mexican policeman finds himself and his partner caught in an often deadly web of corruption; a pair of DEA agents work undercover in a sordid and dangerous part of San Diego; a wealthy drug baron living in upscale, suburban America is arrested and learns how quickly his unknowing and pampered wife takes over his business; and the U.S. President's new drug czar must deal with his increasingly drug-addicted...

A cash-strapped Nicolas Cage agrees to make a paid appearance at a billionaire mega fan's birthday party, but is really a snitch for the CIA since the billionaire fan is a drug kingpin and gets cast in a Tarantino movie.

Webb stumbles onto a story which leads to the shady origins of the men who started the crack epidemic on the nation's streets, and further alleges that the CIA was aware of major dealers who were smuggling cocaine into the U.S., and using the profits to arm rebels fighting in Nicaragua. Despite warnings from drug kingpins and CIA operatives to stop his investigation, Webb keeps digging to uncover a conspiracy with explosive implications.