Kate Maxwell is a saloon proprietress caught between her feelings for suave cattle promoter Jim and the town's sheriff. There's plenty more about Jim that Kate doesn't know, and by the time she finds out the truth, both she and the town are in grave danger. Now Kate and the sheriff have to battle overwhelming odds to set things right.

A plains drifter cowboy single-handedly rescues a local nun from a gang of attackers, but discovers that the she is not what she seems.

As Destry, a mild-mannered deputy who doesn't like guns, Stewart is called to restore order to the hopelessly corrupt frontier town of Bottleneck. Though reluctant to undertake such an enormous task, he's soon roped into action after meeting the seductive Frenchy (Dietrich), an alluring saloon girl who belts out unforgettable show-stoppers like "The Boys in the Back Room," while winning the hero's heart.