Seventeen-year-old Bianca Piper may not be the prettiest girl in her high school, but she has a loyal group of friends, a biting wit, and a spot-on BS detector. She's also way too smart to fall for the charms of man-slut and slimy school hottie Wesley Rush, who calls Bianca the Duff--the Designated Ugly Fat Friend--of her crew. But things aren't so great at home and Bianca, desperate for a distraction, ends up kissing Wesley. Worse, she likes it....