Based on the true story of the doctor who discovered chronic traumatic encephalopathy, known as CTE in football players, and the uphill battle he faced in bringing the information to the public.

Plant-like extraterrestrials have invaded Santa Mira, a small town in California, replicating the villagers in giant seed "pods" and taking possession of their souls while they sleep. In a terrifying race, for his life, Dr. Miles Bennell escapes to warn the world of the deadly invasion of the pod people.